An anti-depression light-wave device includes a switch module, a control module and a light source module, wherein the switch module is connected to a regulatory module by the control module and the regulatory module is connected to the light source module. It provides a voltage of 2.3-2.5V for the light source module. The light produced by the light source is monochromatic light of visible light. Preferable wave range is 590-630 nm of the orange light. Moreover, a light source is provided. The anti-depression light-wave device is used as a device to prevent and treat depression. A significant improvement effect for depression, reduction of side effects of antidepressants is shown.