This refers to renin inhibitors of the General formula (1), Intermediates involved in their Synthesis, their pharmaceutically acceptable Salts and Pharmaceutical compositions containing them.It also relates to a process for the preparation of compounds of the General formula (1), where all symbols are as defined in the specification, their tautomeric forms, pharmaceutically acceptable salts thereof, Pharmaceutical compositions containing them, and Intermediate involved Specially created in their Synthesis.Claim 1: The Compound represented by the formula (1), including its stereoisomers, and taut\u00f3meros solvates, where X is selected from the Group comprising independently - CH2 -, o, and S (o) P P when it appears in each case is selected regardless of the integers 0, 1, 2 n Selected is an integer of 12 M is an atom of nitrogen or carbon R3 is selected independently at each occurrence of the Group comprising Oh, CN, halogen, N3, NO2, COOH, ocf2h, CF3, alkyl - 6 alquenilo C1, C2 C1 - 6, 6 - alkoxy alkyl C1, C (o) - 6, C (or rent) or - C1 - 6S (o) P C1 - 6 or - alkyl groups (CH2) 1 - 2 - alkyl Q represents an integer of 1 - 4 and P is as defined above r1 is alkyl, optionally substituted cycloalkyl groups C1 - C3 - 6 or 7 R2 is an aryl substituted Ring or a Ring or insustituido heterociclilo replaced or insustituido containing 1 3 heteroatoms selected irrespective of OxygenSulphur and Nitrogen or in an alternative implementation, R1 and R2 together with the nitrogen Atom to which together form a single FUSED Heterocyclic Ring or optionally substituted saturated or partially saturated unsaturated, which is optionally substituted and contains option At present, one or more additional heteroatoms selected nitrogenOxygen or Sulphur or comprises a Group - So - or - SO2 - Where one or more of these nitrogen Atoms is replaced with an optionally substituted alkyl groups selected alcanoilo C1 C1 - 8 8 - or aryl or Heterocyclic Group, an optionally substituted.Claim 17: an int
