The present invention discloses compounds for the treatment of cancer and its application. These compounds comprises one of the following compound:Ammonium pyrrolidinedithiocarbamate、Bay 11-7085、BIO、Brefeldin A、(+)-Butaclamol、Calcimycin、Calmidazolium chloride、Chelerythrine chloride、CK2 Inhibitor 2、CGP-74514A hydrochloride、CGS-12066A meleate、Dequalinium dichloride、Dihydroouabain、Diphenyleneiodonium chloride、Emetine dihydrochloride hydrate、GR 127935 hydrochloride、Nifedipine、6-Nitroso-1,2-benzopyrone、Palmitoyl-DL-Carnitine chloride、Parthenolide、PD 169316、1,10-Phenanthroline monohydrate、4-Phenyl-3-furoxancarbonitrile、Prazosin hydrochloride、Protoporphyrin IX disodium、Quinacrine dihydrochloride、Quabain、Retinoic acid p-hydroxyanilide、Rottlerin、Sanguinarine chloride、Tetraethylthium disulfide and SU 9516. The invention also provides new uses of these compounds, compounds such as for the preparation of the treatment of cancer, inhibit cancer cell, cancer stem cell growth and provides a new pharmaceutical composition for treating cancers本發明係一種用於治療癌症的化合物及其應用。該等化合物係包含吡咯烷二硫代氨基甲酸銨、(E)3-((4-t-丁苯基)硫醯)-2-丙烯腈、(2’Z,3’E)-6-溴靛玉紅-3-肟、γ-4-二烴基-2-(6-烴基-1-庚烯基)-4-環戊烷巴豆酸λ-內酯、布他拉莫、凱西黴素、1-[雙(4-氯苯基)甲基]-3-[2-(2,4-雙氯苯基)-2-(2,4-雙氯苯氧基)乙基]-1氫-咪唑鹽類、氯化白屈菜赤堿、4,5,6,7-四溴苯并咪唑、N2-(順-2-胺基環己基)-N6-(3-氯苯基)-9-乙基-9H-嘌呤-2,6-二胺鹽酸鹽、7-三氟甲基-4-(4-甲基-1- -哌肼基)吡咯-[1,2-a]喹喔啉蘋果酸鹽、地喹氯銨、二氫烏本、碘化二苯碘鹽、二鹽酸吐根堿、N-[4-甲氧基-3-(4-甲基-1-哌嗪基)苯基]-2-甲基-4-(5-甲基-1,2,4-口咢二唑)-1,1-二苯基-4-羧基醯胺水合鹽酸鹽、3,4-二氫-2,2-二甲基-2H-駢[1,2-B]吡喃-5,6-二酮、耐克螺、尼非得品、6-亞硝基-1,2-苯並吡喃酮、棕櫚醯-DL-肉鹼鹽、小白菊內酯、4-(4-氟苯基)-2-(4-硝基苯)-5-(4-吡啶)-1H-咪唑、1,10-一水二氮雜菲、4-苯基-3-氧化呋咱羧腈、鹽酸呱唑嗪、前吡喀紫質六二鈉、奎納克林二鹽酸鹽、烏本苷、維它命A酸對-烴基苯胺、呂宋揪夾粉素、血根堿、二硫化四乙基硫碳醯胺及3-[1-(3H-咪唑-4-yl)-meth(Z)-炔基]-5-甲氧基-1,3-二氫-2吲哚;本發明亦提供該等化合物之新用途,係將該等化合物用於製備治療癌症、抑制癌細胞、癌幹細胞生長之醫藥組合物的新穎用途。
