The present application relates to prodrug derivatives of 2-amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl} thio)-4-[4-(2-hydroxyethoxy)phenyl]pyridine-3,5-dicarbonitrile, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of cardiovascular disorders.本發明係關於2-胺基-6-({[2-(4-氯苯基)-1,3-噻唑-4-基]甲基}硫基)-4-[4-(2-羥基乙氧基)苯基]吡啶-3,5-二腈之前藥衍生物、其製備方法、其用於治療及/或預防疾病之用途,及其用於製造藥劑供治療及/或預防疾病之用途,特別是心血管疾病。