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Erythropoietin-derived peptides and methods of protecting cells from oxidative damage induced by reactive oxygen species
专利权人:
SYLUS CO.; LTD.
发明人:
Che il Moon,Seung Yoo,Chang-Hun Lee,So Kim,Deok Lee
申请号:
US16551060
公开号:
US10808018B2
申请日:
2019.08.26
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A peptide is described herein that has: (i) a simple structure compared to existing natural human erythropoietin, thus capable of easily passing through a tissue-blood barrier, (ii) excellent bioactivity with respect to cell-protecting activity, (iii) a low manufacturing cost, thus being economically advantageous, and (iv) no side effects on cell proliferation. Also, a pharmaceutical composition comprising the erythropoietin-derived peptide described herein as an active ingredient is described. The pharmaceutical composition may be used for preventing or treating cell damage-related illnesses, such as stroke, mechanical damage or ischemic damage to the nervous system, myocardial infarction, retinal damage, and diabetes. Also, the described pharmaceutical composition may be used for preventing cell damage.
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