Hormann, Robert E.,Shulman, Inna,Rodel, Eva,Hilfiker, Rolf,Depaul, Susan M.
申请号：
AU2013201096
公开号：
AU2013201096A1
申请日:
2012.09.07
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
#$%^&*AU2013201096A120130328.pdf#####- 93 Abstract The present disclosure provides crystalline polymorphic and amorphous forms of (R)-3,5-dimethyl-benzoic acid N-(l -tert-butyl-butyl)-N'-(2-ethyl-3-methoxybenzoyl)-hydrazide (Compound 1) or (S)-3,5-dimethyl-benzoic acid N-(1-tert-butylbutyl)-N'-(2-ethyl-3-methoxy-benzoyl)-hydrazide (Compound 2). The present disclosure further provides compositions comprising crystalline polymorphic and amorphous forms of Compound 1 or Compound 2 and an excipient, methods of making crystalline polymorphic or amorphous forms of Compound 1 or Compound 2, and methods of using crystalline polymorphic or amorphous forms of Compound I or Compound 2 to regulate gene expression in a cell or in a subject.
