ALTMAN, MICHAEL D.,CHILDERS, KALEEN KONRAD,DI FRANCESCO, MARIA EMILIA,ELLIS, JOHN MICHAEL,FISCHER, CHRISTIAN,GRIMM, JONATHAN,HAIDLE, ANDREW M.,KATTAR, SOLOMON D.,NORTHRUP, ALAN B.,OTTE, RYAN D.,PETROC
申请号:
EP12782298
公开号:
EP2706853A4
申请日:
2012.05.04
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The present invention provides novel pyrimidine amines of formula I which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis and cancer.