ALTMAN, MICHAEL D.,DI FRANCESCO, MARIA EMILIA,HAIDLE, ANDREW M.,OTTE, RYAN D.,ELLIS, JOHN MICHAEL,CHILDERS, KALEEN KONRAD,NORTHRUP, ALAN B.,YANG, LIPING
申请号:
CA2834062
公开号:
CA2834062A1
申请日:
2012.05.04
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention provides novel pyrimidine amines of formula I which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis, and cancer.