DESCHENES, DENIS,ALTMAN, MICHAEL D.,ELLIS, JOHN MICHAEL,FISCHER, CHRISTIAN,HAIDLE, ANDREW M.,KATTAR, SOLOMON D.,NORTHRUP, ALAN B.,SCHELL, ADAM J.,SMITH, GRAHAM F.,TAOKA, BRANDON M.,BIENSTOCK, COREY,DI
申请号:
TW101116553
公开号:
TW201249829A
申请日:
2012.05.09
申请国别(地区):
TW
年份:
2012
代理人:
摘要:
The present invention provides novel pyrimidine amines of formula I which are potent inhibitors of spleen tyrosine kinase, or are prodrugs thereof, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis and cancer.