A method and device for determining a flow situation in a vessel are disclosed. According to an embodiment of the method, a first image data set containing image information relating to the vessel is used and a vascular tree of the vessel is segmented based upon the first image data set. An organ is also segmented based upon the first image data set or of a second image data set and the organ is assigned at least one area of a parenchyma of the organ. Via texture analysis, a texture of the area of the organ is determined and, depending on the texture, the area of the organ is assigned a flow characteristic. Depending on the vascular tree and the flow characteristic assigned to the area of the organ, a value of a measured variable characteristic of the flow situation within the vessel is then determined via a numerical method.
