To provide a medicine delivery device capable of omitting fractions properly, without aligning an orientation of a pocket and an orientation of a wide edge by a user, in filling of a PTP sheet in a medicine storage cassette.SOLUTION: There are states of a PTP sheet 100 which are a first state in which a pocket is directed to a front surface and a wide edge 100a is at a left position, a second state in which the pocket is directed to a front surface and the wide edge 100a is at a right position, a third state in which the pocket is directed to a rear surface and the wide edge 100a is at the left position, and a fourth state in which the pocket is directed to the rear surface and the wide edge 100a is at the right position. Regardless of a state of a beginning PTP sheet 100 delivered, two state changes can be generated, out of a state change by rotation around a long axis, a state change by rotation around a short axis, and a state change by rotation around a normal line, thereby aligning a state of the PTP sheets to any one state.SELECTED DRAWING: Figure 17【課題】 薬剤収容カセットへのPTPシートの充填時に、ポケットの向きや幅広縁の向きを一定方向にユーザーが整えなくても、適切に端数カットができる薬剤払出装置を提供する。【解決手段】 PTPシート100の状態には、ポケットが表向きで広幅縁100aが左位置の第1状態と、ポケットが表向きで広幅縁100aが右位置の第2状態と、ポケットが裏向きで広幅縁100aが左位置の第3状態と、ポケットが裏向きで広幅縁100aが右位置の第4状態とがある。払い出された先頭のPTPシート100がどの状態であっても、長軸回りでの回動による状態変化と、短軸回りでの回動による状態変化と、法線回りでの回動による状態変化のうち2つの状態変化を生じさせることで、いずれか1つの状態に揃えることができる。【選択図】図17