SEONG, Jae Young,HWANG, Jong-Ik,KIM, Dong-Hoon,SON, Gi Hoon,LEE, Yoo-Na,YUN, Seongsik,REYES-ALCARAZ, Arfaxad
申请号：
EP16871028
公开号：
EP3384920A4
申请日:
2016.11.30
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
The present invention relates to spexin-based agonists specific for galanin receptor type 2 and use thereof. More specifically, the present invention provides peptide-based agonists with high specificity for galanin receptor type 2 and improved stability. The peptide-based agonists are involved in the regulation of in vivo physiological functions, such as food intake, anxiety, emotion, and addiction, for which galanin receptors type 2 is responsible, to effectively suppress appetite, help recover from anxiety disorder, and reduce pleasure addiction. Therefore, the peptide-based agonists can be used to prevent or treat galanin receptor type 2-mediated diseases.
