Jae Young SEONG,Jong-Ik HWANG,Dong-Hoon KIM,Gi Hoon SON,Yoo-Na LEE,Seongsik YUN,Arfaxad REYES-ALCARAZ
申请号：
US16511976
公开号：
US20200010509A1
申请日:
2019.07.15
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to spexin-based agonists specific for galanin receptor type 2 and use thereof. More specifically, the present invention provides peptide-based agonists with high specificity for galanin receptor type 2 and improved stability. The peptide-based agonists are involved in the regulation of in vivo physiological functions, such as food intake, anxiety, emotion, and addiction, for which galanin receptors type 2 is responsible, to effectively suppress appetite, help recover from anxiety disorder, and reduce pleasure addiction. Therefore, the peptide-based agonists can be used to prevent or treat galanin receptor type 2-mediated diseases.
