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AGONIST OF SPEXIN-BASED GALANIN TYPE 2 RECEPTOR AND USE THEREOF
专利权人:
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
发明人:
Jae Young SEONG,Jong-Ik HWANG,Dong-Hoon KIM,Gi Hoon SON,Yoo-Na LEE,Seongsik YUN,Arfaxad REYES-ALCARAZ
申请号:
US15771078
公开号:
US20180319841A1
申请日:
2016.11.30
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to spexin-based agonists specific for galanin receptor type 2 and use thereof. More specifically, the present invention provides peptide-based agonists with high specificity for galanin receptor type 2 and improved stability. The peptide-based agonists are involved in the regulation of in vivo physiological functions, such as food intake, anxiety, emotion, and addiction, for which galanin receptors type 2 is responsible, to effectively suppress appetite, help recover from anxiety disorder, and reduce pleasure addiction. Therefore, the peptide-based agonists can be used to prevent or treat galanin receptor type 2-mediated diseases.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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