Commonwealth Scientific and Industrial Research Organisation
发明人:
Nilsson, Susan Kaye,Haylock, David Norman,Cao, Benjamin Ben Ming
申请号:
AU2015362089
公开号:
AU2015362089A1
申请日:
2015.12.11
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
Haematopoietic stem cell mobilization is a process whereby haematopoietic stem cells are stimulated out of the bone marrow space. Before HSC can mobilize, they must be dislodged and released from the BM stem cell niche in which they reside and are retained by adhesive interactions. Accordingly, in an aspect of the present invention there is provided a method for enhancing dislodgement of HSC and their precursors and progenitors thereof from a BM stem cell binding ligand