Methods and compositions are presented for mobilizing hematopoietic stem cells (HSC) and for mobilizing T lymphocytes from the bone marrow and other compartments use of the mobilized HSCs for HSC transplantation and mobilized T lymphocytes for T cell immunotherapy for enhancing engraftment of transplanted HSCs and transferred T cells and for enhancing recovery of hematopoietic system function following HSC transplantation or for enhancing engraftment and/or persistence of T cells following transfer for T cell immunotherapy.
