There are provided amphiphilic biodegradable copolymers comprings a hydrophilic backbone with pendant aliphatic groups as the hydrophobic component. The polymers form nanoscale molecular aggregates in aqueous environments, which have hydrophobic interiors that are capable of solubilizing insoluble organic compounds and disrupting viral coat proteins. The polymers optionally feature reactive functional groups that provide attachment points for antibodies, ligands, and other targeting moieties which mediate adherence of the aggregate to a viral target.本發明提供兩性分子可生物降解的共聚物,其含有具有側鏈脂肪族基團作為疏水成分的親水性主鏈。該聚合物在水環境中形成納米大小分子聚集物,其具有疏水內部,其能溶解不溶的有機化合物並且破裂病毒包衣蛋白。聚合物任選地表現反應性官能團的特徵,其提供抗體、配體和其他調節聚集物黏附到病毒目標的靶向部分的連接點。
