Nicholas Brian Raffaele;Scott J. Hecker;Jeff Stebbins;Brett C. Bookser;Mark D. Erion;Serge H. Boyer;Venkat Reddy Mali;K. RAJA REDDY
发明人:
K. RAJA REDDY,Jeff Stebbins,Serge H. Boyer,Mark D. Erion,Scott J. Hecker,Nicholas Brian Raffaele,Brett C. Bookser,Venkat Reddy Mali
申请号：
US13458452
公开号：
US20120270842A1
申请日:
2012.04.27
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention pertains to use of DGAT-1 inhibitors to treat and/or prevent overweight, obesity and various diseases and disorders associated therewith. Other conditions also can be ameliorated or avoided, such as high postprandial triglycerides or diet-related hypertriglyceridemia, cardiovascular risk associated with excessive triglycerides, and insulin resistance/glucose intolerance in overweight patients, those with diabetes or other glucose metabolic disorders such as Syndrome X and/or polycystic ovary disease. Compounds and compositions suitable for use in the disclosed methods are also provided.
