您的位置: 首页 > 农业专利 > 详情页

FINAFLOXACINE À UTILISER DANS LE TRAITEMENT D'INFECTIONS DES VOIES URINAIRES
专利权人:
MERLION PHARMACEUTICALS PTE LTD
发明人:
BENTLEY, Christine,FISCHER, Carsten,LÜCKERMANN, Mark,VENTE, Andreas,WOHLERT, Sven-eric
申请号:
IBIB2015/058660
公开号:
WO2016/110754A1
申请日:
2015.11.10
申请国别(地区):
IB
年份:
2016
代理人:
摘要:
It was found that finafloxacin eradicates pathogens from patients suffering from bacterial infections like urinary tract infections and pyelonephritis more quickly than other fluoroquinolones regularly used for the treatment of these patients. Due to the efficacy of finafloxacin reduced treatment durations without increasing the daily dosage of finafloxacin and at the same time no or shorter stays in hospital are realizable, thus improving patient convenience and significantly lowering the costs of hospitalization and treatment. Reduced hospitalization periods do also clearly reduce the risk of nosocomial infections and of generating drug-resistant strains through extended therapy. The inventive treatment regimens comprise an oral finafloxacin administration for 1-5 days or a parenteral finafloxacin administration for 1-5 days for use in the treatment of a complicated urinary tract infection or pyelonephritis. However, a prior short parenteral administration of finafloxacin (e.g. 3 days) in combination with an oral administration (e.g. 2 days) may be applied, if necessary in case of really severe infections. The present invention further relates to a novel treatment regime for the treatment of uncomplicated UTI whereby a single oral finafloxacin dose is considered to be sufficient to effectively treat patients with uncomplicated UTI.La présente invention concerne la découverte selon laquelle la finafloxacine éradique les agents pathogènes chez des patients atteints d'infections bactériennes, telles que les infections des voies urinaires et la pyélonéphrite, plus rapidement que d'autres fluoroquinolones régulièrement utilisées pour traiter ces patients. En raison de l'efficacité de la finafloxacine, il est possible de recourir à des durées réduites de traitement sans augmenter la dose quotidienne de finafloxacine, avec parallèlement aucune hospitalisation ou une hospitalisation plus courte, ce qui permet d'améliorer le confort du patient et de réduire considérablemen
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充