A litter box for pets comprises a lower tray (2) adapted to receive and contain liquid feces with no leakage and having a closed first bottom wall (4) and an open first upper peripheral edge (5), an upper tray (3) having a second bottom wall (6) with a grid-shaped portion (10) with meshes (11) of predetermined surface extension to allow the passage of urine from the upper tray (3) to the lower tray (2) and an outer second peripheral edge (7) sized to rest on the first peripheral edge (5) and hold the second bottom wall (6) raised with respect to the first bottom wall (4), a litter (14) distributed in the upper tray (3) in an amount sufficient to cover at least the grid-shaped portion (10) and comprising a loose draining material for the at least partial drainage of urine constituted by a plurality of pads (15) in a non-absorbent and washable material and having a surface extension greater than that of the meshes (11) of the grid-shaped portion (10).