PROBLEM TO BE SOLVED: To provide a dialysis agent suppressing inconvenience due to variation in the amount of components contained in a granular material while improving production efficiency, and to provide a method for manufacturing the dialysis agent.SOLUTION: The method for manufacturing the dialysis agent obtained by mixing the granular material 4 containing sodium chloride, potassium chloride, calcium chloride, magnesium chloride and sodium acetate as components includes a mixing step of mixing the components in a state of excluding a part or the whole of the sodium chloride out of the components, and a granulation step of granulating the granular material from a mixture obtained in the mixing step. Moisture required for forming granulated particles by wet granulation in the granulation process is acquired by spraying humidified gas humidified to the amount of saturated steam or less.