Gene transfer in chicken bursal stem cells

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专利权人:

FRED HUTCHINSON CANCER RESEARCH CENTER

发明人:

NEIMAN PAUL E.

申请号：

US20010025199

公开号：

US6946266(B2)

申请日:

2001.12.18

申请国别(地区):

美国

年份:

2005

代理人:

摘要：

The invention relates to a method of expressing proteins in higher eukaryotes in vitro. In general, the invention sets forth a method of expressing exogenous proteins as fusion partners with the immunoglobulin molecules of avian species specifically chickens. The technology involves, in one embodiment, retroviral-mediated gene transfer and transplantation of stem cells from the Bursa of Fabricus in chickens.

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http://www.ckcest.cn/home/