Jana Buccola,Joel Harrington,Syed Hossainy,Mary Beth Kossuth,Annie Liu,James Oberhauser,Fuh-Wei Tang
申请号:
US15590817
公开号:
US20180325707A1
申请日:
2017.05.09
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A method of accelerated aging of bioresorbable polymer scaffolds including exposing the scaffold to water is disclosed. The scaffold is exposed to water at a controlled temperature for a selected aging time. The functional outputs, such as radial strength, expandability, and % recoil obtained from aged scaffolds predict those of real-time aging of the scaffold. The accelerated aging factor, which is the required shelf life divided by the aging time, is significantly higher for poly(L-lactide) scaffolds tested than thermal aging.