DERIVES DE DIOXYDE D'IMINOTHIADIAZINANE UTILISES COMME INHIBITEURS DE LA PLASMEPSINE V

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专利权人:

UCB BIOPHARMA SPRL

发明人:

DE HARO GARCIA, TERESA,LOWE, MARTIN ALEXANDER,MACCOSS, MALCOLM,TAYLOR, RICHARD DAVID,ZHU, ZHAONING

申请号：

CA3015271

公开号：

CA3015271A1

申请日:

2017.02.22

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

A series of 3-imino-5-methyl-1,2,4-thiadiazinane 1,1-dioxide derivatives of formula (I),substituted in the 5-position by a phenyl moietywhich in turn is meta-substituted by an optionallysubstituted fused bicyclic heteroaromatic ringsystem containing at least one nitrogen atom, beingselective inhibitors of plasmepsin V activity, arebeneficial as pharmaceutical agents, especially in thetreatment of malaria.

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