DERIVES D'IMINOTETRAHYDROPYRIMIDINONE UTILISES COMME INHIBITEURS DE PLASMEPSINE V

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专利权人:

UCB BIOPHARMA SPRL

发明人:

CHARLTON, REBECCA LOUISE,DE HARO GARCIA, TERESA,LOWE, MARTIN ALEXANDER,MACCOSS, MALCOLM,MORGAN, TREVOR,TAYLOR, RICHARD DAVID,ZHU, ZHAONING

申请号：

CA3005809

公开号：

CA3005809A1

申请日:

2016.11.24

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

A series of 2-imino-6-methyltetrahydropyrimidin-4(lH)-one derivatives, substituted in the 6-position by a phenyl moiety which in turn is meta-substituted by an optionally substituted unsaturated fused bicyclic ring system containing at least one nitrogen atom, being selective inhibitors of plasmepsin V activity, are beneficial as pharmaceutical agents, especially in the treatment of malaria.

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中国工程科技知识中心

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