Biochemistry reactive materialand device for eliminating low-density lipoprotein (LDL) and method for treating blood or plasma ex vivo to eliminate low-density lipoprotein therein农业专利-农业专业知识服务系统

发明人:: TSAI, PEI YI,蔡佩宜,蔡佩宜,CHEN, CHIH HUNG,陈志宏,陳志宏,LIN, YI HUNG,林溢泓,林溢泓,HUANG, CHIH CHIEH,黄志杰,黃志傑,SHEN, HSIN HSIN,沈欣欣,沈欣欣,KE, LIANG YIN,柯良胤,柯良胤,CHEN, CHU HUANG,陈珠璜,陳珠璜

摘要：: The present invention provides a biochemistry reactive material, including: a substrate an enzyme compostion immobilize on the substrate, wherein the enzyme compostion is selected from a group consisting of: a first enzyme for eliminating a carbohydrate group of a electronegative low-density lipoprotein (LDL) a second enzyme for eliminating ceramide carried by a electronegative low-density lipoprotein (LDL) and the combination thereof, wherein the biochemistry reactive material is capable of eliminating low-density lipoprotein (LDL).本發明提供一種生化反應材料,包括:一基材;以及一酵素組成物固定於該基材上,其中,該酵素組成物係擇自於由下列所組成之群組:一用以清除陰電性低密度脂蛋白(electronegative low-density lipoprotein,electronegative LDL;簡稱L5)之醣基的第一酵素;一用以清除陰電性低密度脂蛋白之所攜帶之神經醯胺(ceramide)的第二酵素;以及上述之組合,其中該生化反應材料具有去除陰電性低密度脂蛋白的能力。