Hemostatic devices for promoting blood clotting can include a substrate (e.g., gauze, textile, sponge, sponge matrix, one or more fibers, etc.), a hemostatic material disposed thereon such as kaolin clay, and a binder material such as crosslinked calcium alginate with a high guluronate monomer molar percentage disposed on the substrate to substantially retain the hemostatic material material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood to accelerate clotting. Moreover, when exposed to blood, the binder has low solubility and retains a majority of the clay material on the gauze. A bandage that can be applied to a bleeding wound to promote blood clotting includes a flexible substrate and a gauze substrate mounted thereon.用於促進血液凝結之止血裝置，其可包含基材(例如紗布、紡織品、海綿、海綿基質、一或多種纖維等)；配置於基材上的止血材料，諸如高嶺黏土；以及配置於基材上以實質上保留止血材料的黏合材料，諸如具有高古洛糖醛酸鹽單體莫耳百分比之交聯褐藻酸鈣。當所述裝置用於治療出血傷口時，至少一部分黏土材料與血液接觸以加快凝結。此外，當暴露於血液時，黏合劑具有低溶解度且將大部分黏土材料保留於紗布上。可用於出血傷口以促進血液凝結之繃帶包含可撓性基材及安放於可撓性基材上的紗布基材。
