A composition for anti-aging or wrinkle improvement of skin comprising mixture of enzyme-treated red ginseng extracts and malt extracts

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专利权人:

发明人:

이태후,양정은,박상용,신헌섭,신지연

申请号：

KR1020110092034

公开号：

KR1014540670000B1

申请日:

2011.09.09

申请国别(地区):

KR

年份:

2014

代理人:

摘要：

PURPOSE: An enzyme-processed red ginseng extract and malt extract containing composition for anti-aging and anti-wrinkle for skin is provided to show anti-aging and anti-wrinkle effects by using an enzyme from Aspergillus, promote collagen biosynthesis from human dermal fibroblasts and suppress MMP-1. CONSTITUTION: An enzyme-processed red ginseng extract and malt extract containing composition for anti-aging and anti-wrinkle for skin is originated from Aspergillus. The composition for anti-aging and anti-wrinkle is manufactured by the following steps: Aspergillus is cultured with a ginseng extract or ginseng powder to increase the productivity of ginsenoside. An enzyme is separated from the culture. The Aspergillus is a Aspergillus niger strain. The Aspergillus niger strain is aspergillus niger 40280, 41018, 41858, 42589, 43547 or 44333. [Reference numerals] (AA) HDF-N cell Proliferation rate(UV non-treated, 48hours)； (BB) HDF-N cell Proliferation rate(UV treated, 48hours)본 발명은 효소-처리 홍삼 추출물과 맥아추출물을 포함하는, 피부노화방지 및 피부주름개선용 조성물을 제공한다. 본 발명의 조성물은 콜라겐 생합성 촉진, MMP-1 억제를 통한 피부 노화방지 및 주름개선효과를 나타내며, 모공의 축소, 피지의 개선 , 효능을 나타내는 동시에 세포 생존율의 변화를 나타내지 아니하여 우수한 안전성(safety)을 나타낸다. 특히, 본 발명의 효소-처리 홍삼 추출물과 맥아 추출물을 배합한 조성물은 종래의 홍삼 추출물 및 효소-처리 홍삼 추출물과 비교하여 개선된 피부노화방지 및 주름개선 효과를 나타낸다.

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