KUCERA, DAVID,HALEY, GREGORY, J.,RUEDEN, ERIK, J.,WANG, TINGMAN,VIERTELHAUS, MARTIN,BLATTER, FRITZ
申请号:
HK10100028.4
公开号:
HK1132429B
申请日:
2010.01.05
申请国别(地区):
HK
年份:
2013
代理人:
摘要:
The present disclosure relates to p-toluene sulfonic acid salt of 5-amino-3-(2′-O-acetyl-3′-deoxy-beta-D-ribofuranosyl)-3H-thiazolo[4,5-d]pyrimidin-2-one and to its use in treating conditions such as viral infections, tumors, and cancer. Also disclosed is a method of preparing the p-toluene sulfonic acid salt of 5-amino-3-(2′-O-acetyl-3′-deoxy-&bgr;-D-ribofuranosyl)-3H-thiazolo[4,5-d]pyrimidin-2-one and methods for producing furanose compounds which are useful intermediates in the preparation of pharmaceutical compounds such as p-toluene sulfonic acid salt of 5-amino-3-(2′-O-acetyl-3′-deoxy-&bgr;-D-ribofuranosyl)-3H-thiazolo[4,5-d]pyrimidin-2-one and the like.