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5-氨基-3-(2'-O-乙酰基-3'-脫氧-BETA-D-腺嘌呤核苷)-3H-噻唑[4,5-D]嘧啶-2-I的對甲基苯磺酸鹽及其製成方法
专利权人:
ANADYS PHARMACEUTICALS INC.
发明人:
KUCERA, DAVID,HALEY, GREGORY, J.,RUEDEN, ERIK, J.,WANG, TINGMAN,VIERTELHAUS, MARTIN,BLATTER, FRITZ
申请号:
HK10100028.4
公开号:
HK1132429B
申请日:
2010.01.05
申请国别(地区):
HK
年份:
2013
代理人:
摘要:
The present disclosure relates to p-toluene sulfonic acid salt of 5-amino-3-(2′-O-acetyl-3′-deoxy-beta-D-ribofuranosyl)-3H-thiazolo[4,5-d]pyrimidin-2-one and to its use in treating conditions such as viral infections, tumors, and cancer. Also disclosed is a method of preparing the p-toluene sulfonic acid salt of 5-amino-3-(2′-O-acetyl-3′-deoxy-&bgr;-D-ribofuranosyl)-3H-thiazolo[4,5-d]pyrimidin-2-one and methods for producing furanose compounds which are useful intermediates in the preparation of pharmaceutical compounds such as p-toluene sulfonic acid salt of 5-amino-3-(2′-O-acetyl-3′-deoxy-&bgr;-D-ribofuranosyl)-3H-thiazolo[4,5-d]pyrimidin-2-one and the like.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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