An energy delivery device for administering tissue therapy includes a housing and an elongated body extending distally from the housing. The energy delivery device also includes a first lumen extending a length of the elongated body. The first lumen is configured to facilitate application of thermal treatment to a target region of tissue. A second lumen extends the length of the elongated body and is configured to facilitate infusion of hydrogels embedded with stem cells to the target region of tissue thermally treated. The energy delivery device further includes a third lumen configured to facilitate delivery of ultraviolet (UV) light to the target region of tissue for curing the hydrogels. A distal end of the elongated body is positioned in proximity to the target region of tissue for enabling successive introduction of the thermal treatment, infusion of the hydrogels, and delivery of the UV light.
