A tissue-ingrowth cuff for stabilization of an implanted catheter against movement, that is placeable onto the catheter by the practitioner at a desired location. The cuff is actuated by the practitioner once moved to its desired location, to grip the catheter. The cuff comprises two body portions securable to each other about a catheter at a practitioner-selected location, by means of complementary locking sections. The two cuff portions are separately slidable along the catheter prior to coupling, but include complementary catheter-gripping sections that cooperate with each other to grip the catheter upon assembly to each other. Tissue-ingrowth material is affixed to the outwardly facing surface of the cuff within a subcutaneous tunnel after catheter implantation and tunneling, thus anchoring the catheter against movement thereafter.