PROCEDE ET SYSTEME POUR GENERER ET ANALYSER AUTOMATIQUEMENT DES CARTES DE RESERVE DE PERFUSION MYOCARDIQUE ET DE DEBIT SANGUIN MYOCARDIQUE ENTIEREMENT QUANTITATIVES PIXEL PAR PIXEL POUR DETECTER UNE MALADIE CARDIAQUE ISCHEMIQUE A L'AIDE D'UNE IMAGERIE PAR RESONANCE MAGNETIQUE DE PERFUSION CARDIAQUE
THE UNITED STATES OF AMERICA, DEPARTMENT OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH;CORSTEM INC.
发明人:
HSU, LI-YUEH,JACOBS, MATTHEW,BENOVOY, MITCHEL,ARAI, ANDREW
申请号:
CA3085303
公开号:
CA3085303A1
申请日:
2019.05.17
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
A computer-implemented method for automatically generatinga fully quantitative myocardial blood flow map, comprising: receivingmyocardial perfusion magnetic resonance imaging (MRI) images and arterialinputfunction (AIF) MRI images; correcting a motion of a heart in the myocardialperfusion MRI images and the AIF MRI images, thereby obtaining motioncorrected myocardial perfusion MRI images and motion corrected AIF images;correcting an intensity of the motion corrected myocardial perfusion MRIimages and an intensity of the motion corrected AIF images, thereby obtainingsurface coil intensity corrected MRI images and surface coil intensitycorrected AIF images; using the surface coil intensity corrected MRI imagesand thesurface coil intensity corrected AIF images, determining time-signal intensitycharacteristics and segmenting a left ventricle myocardial tissue region; andgenerating the myocardial blood flow map using the motion correctedmyocardial perfusion MRI images, the left ventricle myocardial tissue regionsegmentation and the time-signal intensity characteristics.