This invention designates the hair fostering medicine where the effect by the rechinoin Acid is utilized sufficiently and that its production manner is offered as topic. This invention offers the hair fostering medicine which includes the rechinoin Acid production cell. In addition, this invention, culturing process and the aforementioned monocyte which obtain the monocyte from the peripheral blood which was picked from the target which prescribes the hair fostering medicine the process which obtains the maturity tree-like cell and, offers the production manner of the hair fostering medicine which is included. Operation according to the hair fostering medicine of this invention, without the rechinoin Acid denaturalizing, being the head intradermal, because the cell discharges the rechinoin Acid continuously, it can promote the hair growing efficiently.本発明は、レチノイン酸による効果が十分に生かされる育毛剤及びその製造方法を提供することを課題とする。本発明は、レチノイン酸産生細胞を含む育毛剤を提供する。また、本発明は、育毛剤を投与する対象から採取した末梢血から単核球を得る工程と、前記単核球を培養して成熟樹状細胞を得る工程と、を含む育毛剤の製造方法を提供する。本発明の育毛剤によれば、レチノイン酸が変性することなく作用し、頭皮内で細胞が継続的にレチノイン酸を放出するので、効率よく発毛を促進できる。