5-PHENYL-ISOXAZOLE-3-CARBOXAMIDES MODULATING HSP90 WITH ANTITUMORAL ACTIVITIES

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专利权人:

SIGMA-TAU RESEARCH SWITZERLAND S.A.

发明人:

GIANNINI, GIUSEPPE,CABRI, WALTER,SIMONI, DANIELE,BARUCCHELLO, RICARDO,CARMINATI, PAOLO,PISANO, CLAUDIO

申请号：

MYPI 2010005887

公开号：

MY150604A

申请日:

2009.06.30

申请国别(地区):

MY

年份:

2014

代理人:

摘要：

THE PRESENT INVENTION RELATES TO FORMULA I COMPOUNDS HAVING ANTITUMOURAL ACTIVITIES THROUGH, AS ONE POSSIBLE BIOLOGICAL TARGET, THE MOLECULAR CHAPERONE HEAT SHOCK PROTEIN 90 (HSP9O) INHIBITION. THE INVENTION INCLUDES THE USE OF SUCH COMPOUNDS IN MEDICINE, IN RELATION TO CANCER DISEASE AS WELL AS OTHER DISEASES WHERE AN INHIBITION OF HSP9O IS RESPONSIVE, AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS.

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中国工程科技知识中心

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