5-PHÉNYL-ISOXAZOLE-3-CARBOXAMIDES MODULANT HSP90 AYANT DES ACTIVITÉS ANTITUMORALES

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专利权人:

SIGMA-TAU RESEARCH SWITZERLAND S.A.

发明人:

申请号：

EP09772448.8

公开号：

EP2310377B1

申请日:

2009.06.30

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

The present invention relates to formula I compounds having antitumoural activities through, as one possible biological target, the molecular chaperone heat shock protein 90 (Hsp90) inhibition. The invention includes the use of such compounds in medicine, in relation to cancer disease as well as other diseases where an inhibition of Hsp90 is responsive, and the pharmaceutical compositions containing such compounds.

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