5-phenyl isoxazole-3-carboxamides modulating hsp90 with anti-tumor activities'

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专利权人:

SIGMA-TAU RESEARCH SWITZERLAND S.A.

发明人:

CLAUDIO PISANO,DANIELE SIMONI,GUISEPPE GIANNINI,PAOLO CARMINATI,RICARDO BARUCCHELLO,WALTER CABRI

申请号：

BRPI0913834

公开号：

BRPI0913834A2

申请日:

2009.06.30

申请国别(地区):

BR

年份:

2015

代理人:

摘要：

The present invention relates to formula I compounds having antitumoural activities through, as one possible biological target, the molecular chaperone heat shock protein 90 (Hsp90) inhibition. The invention includes the use of such compounds in medicine, in relation to cancer disease as well as other diseases where an inhibition of Hsp90 is responsive, and the pharmaceutical compositions containing such compounds.

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