LERCHEN HANS GEORG,EL SHEIKH SHERIF,STELTE LUDWIG BEATRIX,SCHUHMACHER JOACHIM,GNOTH MARK
申请号：
IN7348/CHENP/2013
公开号：
IN2013CN07348A
申请日:
2013.09.12
申请国别(地区):
IN
年份:
2014
代理人:
摘要：
The present application relates to new derivatives substituted on the N terminus by a carboxyalkyl group of monomethylauristatin E and monomethylauristatin F to processes for preparing these derivatives to the use of these derivatives for treating and/or preventing diseases and to the use of these derivatives for producing medicaments for treating and/or preventing diseases more particularly hyperproliferative and/or angiogenic disorders such as cancer disorders for example. Such treatments may be applied as a monotherapy or else in combination with other medicaments or further therapeutic measures.
