SEIDERS THOMAS JON,HUTCHINSON JOHN HOWARD,ROPPE JEFFREY ROGER,WANG BOWEI,PARR TIMOTHY,ARRUDA JEANNIE M
申请号:
NZ59682610
公开号:
NZ596826A
申请日:
2010.06.03
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
596826 Disclosed herein are compounds of Formula (I), wherein the variables are defined in the specification, and the use thereof in the treatment of cancer or fibrosis. In certain embodiments the compound is 1-{ 4’-[3-methyl-4((R)-1-phenyl-ethoxycarbonylamino)-isoxazol-5-yl]-biphenyl-4-yl} -cyclopropanecarboxylic acid, or (3-methyl-5-{ 4’-[1-(1H-tetrazol-yl)-cyclopropyl]-bipheny1-yl} -isoxazol-4-yl)-carbamic acid (R)-1-phenyl-ethyl ester.