A method of preparing drug agglomerates includes adding a drug powder to a first solvent to form a first solution, spraying a second solvent to the first solution to form a second solution. The drug powder undergoes nucleation to form drug agglomerates. Finally, the drug agglomerates are isolated from the second solution.一種製備藥物凝集體的方法包含添加一粉末狀藥物至一第一溶劑以形成一第一溶液,再向該第一溶液噴灑一第二溶劑以形成一第二溶液,其中該粉末狀藥物進行成核作用以形成一藥物凝集體,以及自該第二溶液分離該藥物凝集體。S110~S130‧‧‧步驟