A therapeutic muscle fixation tape including medicinal substances is provided to protect weakened or relaxed muscles, to allow medicinal treatment with effect of taping treatment, to soften pains from the damaged body parts, to prevent secondary muscle damages through muscle supporting effect of tape as well as muscle stiffness induced by pains, to facilitate blood or body fluids circulation by applying anti-inflammatory agent and vasodilator, and to enhance therapeutic effect of muscle fixation tape. The therapeutic muscle fixation tape including medicinal substances comprises: a fabric sheet(11) on the top surface of tape; an adhesion layer(12) on the one side of the fabric sheet(11) comprising acrylic adhesive and compound medicinal substances comprising 1 type of surface and local anesthetic selected from procaine and lidocaine, 1~2 types of anti-inflammatory agent selected from ketopropen, piroxicam, tenoxicam, diclofenac, ibuprofen, and calcitonin, and 1~2 types of vasodilator selected from torental, me
