MENET, CHRISTEL JEANNE MARIE,HODGES, ALASTAIR JAMES,VATER, HUW DAVID
申请号：
CA2833963
公开号：
CA2833963C
申请日:
2012.04.26
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
Novel pyrrazolopyridines according to Formula I, able to inhibit JAK are disclosed, these compounds may be prepared as a pharmaceutical composition, and may be used for the prophylaxis and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, allergy, inflammatory conditions, autoimmune diseases, proliferative diseases, transplant rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6 or interferons.
