Christel Jeanne Marie Menet;Alastair James Hodges;Huw David Vater
发明人:
Christel Jeanne Marie Menet,Alastair James Hodges,Huw David Vater
申请号：
US14114218
公开号：
US20140051677A1
申请日:
2012.04.26
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Novel pyrrazolopyridines according to Formula I, able to inhibit JAK are disclosed, these compounds may be prepared as a pharmaceutical composition, and may be used for the prophylaxis and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, allergy, inflammatory conditions, autoimmune diseases, proliferative diseases, transplant rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6 or interferons.
