BISCHOFF, FRANCOIS PAUL,VELTER, ADRIANA INGRID,VAN BRANDT, SVEN FRANCISCUS ANNA,BERTHELOT, DIDIER JEAN-CLAUDE
申请号：
CA2827969
公开号：
CA2827969A1
申请日:
2012.03.22
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The present invention is concerned with novel substituted triazolyl piperazine and triazolyl piperidine derivatives of Formula (I) wherein R1, R2, R3, R4a, R4b, R5, X, Y1, Y2, L1, and L2 have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
