Didier Jean-Claude Berthelot;Sven Franciscus Anna Van Brandt;Adriana Ingrid Velter;Francois Paul Bischoff
发明人:
Francois Paul Bischoff,Adriana Ingrid Velter,Sven Franciscus Anna Van Brandt,Didier Jean-Claude Berthelot
申请号：
US14005598
公开号：
US08987276B2
申请日:
2012.03.22
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention is concerned with novel substituted triazolyl piperazine and triazolyl piperidine derivatives of Formula (I)wherein R1, R2, R3, R4a, R4b, R5, X, Y1, Y2, L1, and L2 have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
