PROBLEM TO BE SOLVED: To provide novel external or internal preparations having excellent collagen production promotion action, MMP inhibitory action, melanin production inhibitory action, cell growth promoting action, and antioxidant action.SOLUTION: Borago officinalis extract has excellent collagen production promoting action, MMP inhibitory action, melanin production inhibitory action, cell growth promoting action, and antioxidant action, as well as is also excellent in stability. Borago officinalis extract can be used not only in the beauty field such as skin aging prevention, but also in the medical field such as inhibition of functional deterioration due to aging, cancer prevention, treatment, and the like, as well as is expected to be applied to foods, cosmetics, quasi-drugs and pharmaceuticals and the like.SELECTED DRAWING: NoneCOPYRIGHT: (C)2020,JPO&INPIT【課題】コラーゲン産生促進作用、ＭＭＰ阻害作用、メラニン生成抑制作用、細胞増殖促進作用及び抗酸化作用に優れた新規な外用剤又は内用剤を提供する。【解決手段】ルリジサの抽出物は、優れたコラーゲン産生促進作用、ＭＭＰ阻害作用、メラニン生成抑制作用、細胞増殖促進作用及び抗酸化作用を有し、安定性にも優れていた。ルリジサの抽出物は、皮膚の老化予防といった美容分野だけでなく、老化による機能低下の抑制、ガンの予防、治療等といった医療分野にも利用でき、食品、化粧品、医薬部外品及び医薬品等への応用が期待される。【選択図】なし
