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Poly(citric acid) functionalized carbon nanotube drug delivery system
专利权人:
Fatemeh Atyabi
发明人:
Fatemeh Atyabi,Mohsen Adeli,Zahra Sobhani,Rassoul Dinarvand,Mohammad Hossein Ghahremani
申请号:
US12870943
公开号:
US08460711B2
申请日:
2010.08.30
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A method for synthesizing carbon nanotube drug carriers and the carbon nanotube drug carriers are disclosed. Initially, carbon nanotubes, nitric acid, and sulfuric acid are mixed to oxidize carbon nanotubes in a first mixture. The oxidized carbon nanotubes are then extracted from the first mixture. The oxidized carbon nanotubes and monohydrated citric acid are mixed to synthesize carbon nanotubes grafted with poly(citric acid) in a second mixture. The carbon nanotubes grafted with poly(citric acid) are then extracted from the second mixture. The carbon nanotubes grafted with poly(citric acid) and 4-(dimethylamino)pyridine are dissolved in anhydrous dimethylformamide in a third mixture. Next, a mixture that comprises a drug is added to the third mixture to synthesize the carbon nanotubes grafted with poly(citric acid) and the drug in a fourth mixture. Then, the carbon nanotubes grafted with poly(citric acid) and the drug are extracted from the fourth mixture.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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