Daniel E. Gerard,Joachim Schoelkopf,Patrick A.C. Gane,Veronika Anna Eberle,Rainer Alles,Maxim Puchkov,Jörg Huwyler
申请号:
US14429492
公开号:
US20150231078A1
申请日:
2013.10.10
申请国别(地区):
US
年份:
2015
代理人:
摘要:
An instantly floating gastroretentive drug formulation comprising at least one functionalized natural and/or synthetic calcium carbonate-comprising mineral and at least one pharmaceutically active ingredient and at least one formulating aid wherein said functionalized natural or synthetic calcium carbonate is a reaction product of natural or synthetic calcium carbonate with carbon dioxide and one or more acids, wherein the carbon dioxide is formed in situ by the acid treatment and/or is supplied from an external source.