A stable liquid pharmaceutical formulation according to the present invention comprises an antibody or antigen-binding fragment thereof; a surfactant; a sugar or derivative thereof; and a buffer. The stable liquid pharmaceutical preparation according to the present invention has a high content of antibodies, has a low viscosity, has excellent long-term storage stability based on excellent stability under accelerated conditions and severe conditions, and is subcutaneously Administration is possible.本発明に係る安定な液体医薬製剤は、抗体またはその抗原結合断片;界面活性剤;糖またはその誘導体;および緩衝剤を含む。本発明に係る安定な液体医薬製剤は、抗体を高含量で含み、且つ、低粘度を有し、加速条件および苛酷条件における優れた安定性を基に長期間保管安定性に優れており、皮下投与が可能である。