ALEXANDER, Rikki Peter,BRACE, Gareth Neil,BROWN, Julien Alistair,CALMIANO, Mark Daniel,CHOVATIA, Praful Tulshi,DELIGNY, Michael,GALLIMORE, Ellen Olivia,HEER, Jag,JACKSON, Victoria Elizabeth,KROEPLIEN,
申请号：
ES14808658
公开号：
ES2755335T3
申请日:
2014.12.08
申请国别(地区):
ES
年份:
2020
代理人:
摘要：
A series of fused tricyclic imidazole derivatives, in particular dihydro-1H-cyclopenta[4,5]imidazo[1,2-a]pyridine derivatives, and analogues thereof, being potent modulators of human TNFα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders； neurological and neurodegenerative disorders； pain and nociceptive disorders； cardiovascular disorders； metabolic disorders； ocular disorders； and oncological disorders.
