A sterilization method of a food cooling device employing a temperature difference effect, includes a sterilizing space to accommodate energy conductive tubes with cold water within and a steam transited to the sterilizing space for a fast temperature difference phenomenon and further a temperature difference effect created by low-temperature fluid inside and steam outside the energy conductive tubes in which the temperature difference effect strengthens lethality to colon bacillus or Salmonella and separates residual food from the energy conductive tubes walls for cleaning effectively delivered by the energy conductive tubes and food healthily processed by the food cooling device.
